A report of four patients with Moebius syndrome: New oral anomalies and challenges in dental management

Hassib, Nehal F.; AbdelKader, Mohamed A.; AbulEzz, Eman A.; Aglan, Mona S.; Temtamy, Samia A.

doi:10.4103/MXE.MXE_15_19

A report of four patients with Moebius syndrome: New oral anomalies and challenges in dental management

Authors

Abstract

Background
Moebius syndrome (MBS MIM # 157900) is mostly a sporadic disorder characterized by nonprogressive congenital facial and eye abduction paresis. Some patients have associated limb anomalies. Orofacial abnormalities are regularly associated with the syndrome.
Aim
The authors report four unrelated Egyptian patients with MBS presented with variable oral and dental abnormalities. New orodental findings of the syndrome were presented.
Materials and methods
Dental management was offered to the needed patient with suitable modifications to fit the case. The four probands were subjected to full medical history taking and extensive clinical and orodental examinations. Restorative and prosthetic management with special modifications was highly recommended.
Results
Results exhibited commonly detected orodental anomalies. Alveolar ridge asymmetry, microdontia, and premature eruption were new findings of the syndrome. Increasingly, dental management improved speech, mastication, and esthetic of the patient.
Conclusion
The detection of new oral findings could expand the phenotype of the syndrome. The appropriate recognition of the disorder provides accurate management and patient satisfactory parameters. The authors noted a positive correlation between severity of orodental anomalies and limb involvement. The authors recommend further orodental evaluation of more patients with MBS, which may help in understanding its etiopathological aspects in correlation with its phenotypic diversity.

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